Impact of Implantation of an LAA Occluder on ANP and BNP Level and Quality of Life

University of Leipzig25 enrolled

Overview

Closure of the LAA by several devices is a alternative therapy to oral anticoagulation in patients with Atrail fibrillation. Nothing is known about the acute influence of a device closure of the LAA on the secretion of ANB nad BNP hormones. Therefore aim of our study is to measure ANB and BNP levvels before and after Implantation of an LAA closure device.

ANB and BNP levels are measured before, directly after and late after 24 h in central or periphereal venous blood from patients undergoing interventional LAA closure.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Atrial Fibrillation

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * patients undergoing LAA closure Exclusion Criteria: * none

Locations (1)

Heart Center Leipzig- University Leipzig

Leipzig, Germany

Outcomes

Primary Outcomes

Change from baseline atrial natriuretic Peptide (ANP)

comparison of ANP level pre and post intervention

Time frame: 24 h post intervention

Data from ClinicalTrials.gov

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