Maternal Periodontal Status and Cytokines in Preeclampsia

Hacer Sahin Aydinyurt80 enrolled

Overview

Background: The purpose of this study is to examine the relationship between maternal preeclampsia and periodontal parameters and the correlation of these two disorders with maternal gingival crevicular fluid levels (GCF) of interleukin (IL)-35, interleukin-37 and interleukin-6. The investigators also investigated their relation to the severity of preeclampsia. Methods: 82 preeclamptic women were recruited to the study (29 healthy pregnant women, 30 mild preeclamptic patient, 23 severe preeclamptic patient ). The clinical periodontal parameters and GCF samples were collected in the first day of puerperium.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Preeclampsia Periodontal Diseases

Interventions

gingival crevicular fluid collectionDIAGNOSTIC_TEST

Eligibility

Medical Language ↔ Plain English

Inclusion Criteria: * Aged between 18 and 45 years * 25 and 40 weeks of gestation. * Healthy pregnants, mild and severe preeclampsia Exclusion Criteria: * Patients with accompanying diseases * multiple gestations * congenital abnormalities were excluded from the study.

Outcomes

Primary Outcomes

maternal periodontal clinical parameters and IL-37 and IL-35 and IL-6 levels

IL-37 IL-35 and IL-6 levels in maternal gingival crevicular fluid levels between the three groups

Time frame: 6 months