Vitamin D has become important for periodontal disease due to play a role in autoimmunity, bone mineral metabolism and inflammation. Our aim was to investigate the relation between serum 25-hydroxy vitamin D levels, clinical periodontal parameters and blood serum biomarkers. The subjects were evaluated in 2 groups as chronic periodontitis (n= 30) and periodontally healthy subjects (n= 30). Periodontal parameters and fasting venous blood samples were taken from the subjects to assess each patient's periodontal status and for biochemical analyses (25-hydroxy vitamin D (25-OH vit D), osteoprotegerin (OPG), receptor activator of nuclear kappa B ligand (RANKL), C-telopeptide (CTx), tumor necrosis factor-α (TNF-α)).
Study Type
OBSERVATIONAL
Enrollment
60
Biochemical parameters
serum TNF-α
Time frame: Baseline
Biochemical parameters
serum CTx
Time frame: Baseline
Biochemical parameters
serum RANKL
Time frame: Baseline
Biochemical parameters
serum OPG
Time frame: Baseline
Biochemical parameters
serum 25-OH vitamin D
Time frame: Baseline
Periodontal parameters
The plaque index (PI)
Time frame: Baseline
Periodontal parameters
gingival index (GI)
Time frame: Baseline
Periodontal parameters
probing depth (PD)
Time frame: Baseline
Periodontal parameters
clinical attachment level (CAL)
Time frame: Baseline
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