Incisional hernia is a common complication in visceral surgery and varies between 11 and 26% in the general surgical population. Patients requiring emergency laparotomy are at high risk for the development of incisional hernia and fascial dehiscence. Among this population the incidence of incisional hernia in patients undergoing emergency surgery varies between 33-54%. Incisional hernias are associated with a high morbidity rate, such as intestinal incarceration, chronic discomfort, pain, and reoperation and typically require implantation of a synthetic mesh in a later second operation. Fascial dehiscence represents an acute form of dehiscence and has been observed in up to 24.1% and is associated with a mortality rate up to 44%. The gold standard for abdominal wall closure during elective and emergency operations is a running slowly absorbable suture. In the elective situation it has been shown that prophylactic mesh implantation in high risk patients reduced the incidence of incisional hernia significantly. The investigators and others have shown that mesh implantation in patients undergoing emergency laparotomy or in contaminated abdominal cavities are safe . With a randomized controlled trial the investigators now aim to compare the incidence of incisional hernia after prophylactic mesh implantation versus standard of care in patients requiring emergency laparotomy.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Enrollment
61
Intra-abdominally Fixation
Intra-abdominal suture
Dep. of Visceral and transplant surgery, Berne University Hospital
Bern, Switzerland
Number of incidence of death
follow-up
Time frame: up to 18 months
Number of patients with hernia free survival
follow-up
Time frame: up to 18 months
Number of patients with postoperative fascial dehiscence
follow-up
Time frame: 30 days
Number of postoperative mortality
survival
Time frame: 90 days
Number of surgical site infections postoperative
follow-up
Time frame: 30 days
Number of postoperative intestinal fistulas
follow-up
Time frame: 30 days
Number of small bowel obstructions
follow-up
Time frame: 18 months
Number of patients with postoperative pain
follow-up
Time frame: 18 months
Number of postoperative mesh infections
follow-up
Time frame: 18 months
Number of postoperative mesh explantations
follow-up
Time frame: 18 months
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