In healthy subjects not receiving or requiring lipid lowering therapy and who do not have diabetes, the use of clinoptilolite (GPUR) will result in a reduction of absorbed dietary cholesterol observed over 6 days of therapy.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
22
randomized, open-label, cross-over study of control vs clinoptilolite with a washout period separating the 2 phases
Atlanta Heart Specialists
Cumming, Georgia, United States
Percent change in fractional cholesterol absorption in human subjects taking clinoptilolite over 6 days
Primary Objective
Time frame: 39 days
Percent change from baseline by gender to determine gender difference in fractional cholesterol absorption rates
Secondary Objective
Time frame: 39 days
Percent change from baseline to end of treatment to evaluate for safety changes in metabolic profile measurements
Secondary Objective
Time frame: 39 days
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