This study will assess the putative advantages of cerebellar stimulation on motor learning abilities of stroke patients. In order to have a control group to refer to, the effect of cerebellar stimulation on healthy young and old participants will also be assessed.
Cerebrovascular accidents (CVA) are the first cause of acquired disability in France. Despite rehabilitation interventions, a great proportion of patients suffers from motor disability in the upper limb. Recently, several studies have shown that post CVA patients exhibit great neural plasticity as a direct consequence of their condition. Interestingly, the transcranial direct current stimulation (tDCS) is a non-invasive electro stimulation technique that allows for a modulation of cerebral activity. It has been shown that when applied to the cerebellum, tDCS increases learning performances of healthy subjects. Yet, motor rehabilitation after a CVA highly relies on motor (re)learning. The cerebellar tDCS thus appear as a promising method to enhance the performance of post-CVA motor learning and consequently the benefits of post-CVA rehabilitation. The current study aims to promote the post CVA neural plasticity by using the tDCS in order to enhance motor learning of the upper limb.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
60
ramp stimulation from 0 to 2 mA followed by 20 minutes of stimulation at 2mA while practicing during 3 of the 4 sessions
ramp stimulation from 0 to 2 mA followed by 30 sec of stimulation at 2mA.
Centre de Recherche Clinique (CRC) - CHSA
Paris, France
RECRUITINGService de Médecine Physique et Rédaptation
Paris, France
NOT_YET_RECRUITINGForce control
Measurement in Newton of the force applied by each finger.
Time frame: Day 1
Force control
Measurement in Newton of the force applied by each finger.
Time frame: Day 2
Force control
Measurement in Newton of the force applied by each finger.
Time frame: Day 3
Force control
Measurement in Newton of the force applied by each finger.
Time frame: Day 10
Overflow
Measurement in ms of the involuntary finger movements.
Time frame: Day 1
Overflow
Measurement in ms of the involuntary finger movements.
Time frame: Day 2
Overflow
Measurement in ms of the involuntary finger movements.
Time frame: Day 3
Overflow
Measurement in ms of the involuntary finger movements.
Time frame: Day 10
Moberg Pick-up Test
Assessment of the functionality of the hand. One score will be given at the end of the test.
Time frame: Day 1
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Moberg Pick-up Test
Assessment of the functionality of the hand. One score will be given at the end of the test.
Time frame: Day 2
Moberg Pick-up Test
Assessment of the functionality of the hand. One score will be given at the end of the test.
Time frame: Day 3
Moberg Pick-up Test
Assessment of the functionality of the hand. One score will be given at the end of the test.
Time frame: Day 10
Action Research Arm Test
Assessment of the upper limb mobility. One score will be given at the end of the test
Time frame: Day 1
Action Research Arm Test
Assessment of the upper limb mobility. One score will be given at the end of the test
Time frame: Day 2
Action Research Arm Test
Assessment of the upper limb mobility. One score will be given at the end of the test
Time frame: Day 3
Action Research Arm Test
Assessment of the upper limb mobility. One score will be given at the end of the test
Time frame: Day 10
Finger time release
Time needed to release the finger force when needed (in ms).
Time frame: Day 1
Finger time release
Time needed to release the finger force when needed (in ms).
Time frame: Day 2
Finger time release
Time needed to release the finger force when needed (in ms).
Time frame: Day 3
Finger time release
Time needed to release the finger force when needed (in ms).
Time frame: Day 10