The impact of a pharmacist's intervention on asthma control has now been well demonstrated, but its effect on inflammatory markers of FENO (Fractional exhaled nitric oxide) in asthmatic patients has been little studied in the literature. The aim of this study is to investigate the impact of a pharmacist's intervention on FENO in patients seen in clinical practice by a pneumologist in a secondary university center.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
SINGLE
Enrollment
68
Pharmacist's intervention with asthmatic patients: * Detailed questionnaire on asthma and treatments (atopy, comorbidities, smoking status, asthma control, adverse effects of treatments, etc.) * Explanation of asthma and inflammation * Explanation of triggers and how to avoid it * Explanation of asthma treatments * Explanation of the inhalation technique with a physical demonstration * Emphasis on treatment adherence * Assessment of comorbidities and their treatment * Emphasis on influenza vaccination
\- Detailed questionnaire on asthma and treatments (atopy, comorbidities, smoking status, asthma control, adverse effects of treatments, etc.)
Change from Baseline FENO (fractional exhaled nitric oxide) at 3 months
Fractional exhaled nitric oxide
Time frame: 3 months
Change from Baseline FEV1 (forced expiratory volume in 1 second) at 3 months
Time frame: 3 months
Change from Baseline FVC (forced vital capacity) at 3 months
Time frame: 3 months
Change from Baseline FEV1/FVC at 3 months
Time frame: 3 months
Change from Baseline ACQ (Asthma Control Questionnaire) at 3 months
Time frame: 3 months
Change from Baseline ACT (Asthma Control Test) at 3 months
Time frame: 3 months
Change from Baseline miniAQLQ (Asthma Quality of Life Questionnaire) at 3 months
Time frame: 3 months
Change from Baseline MARS (Medication Adherence Report Scale) at 3 months
Measure of treatment adherence
Time frame: 3 months
Change from Baseline MRA (Medication Refill Adherence) at 3 months
Measure of treatment adherence
Time frame: 3 months
Change from Baseline score of the inhalation technique at 3 months
Time frame: 3 months
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Change from Baseline number of severe exacerbations (during the 3 previous months) at 3 months
Severe exacerbations are asthma exacerbations requiring oral corticosteroids
Time frame: 3 months
Change from Baseline smoking status at 3 months
Smoking status is recorded as non-smoker, ex-smoker, current smoker
Time frame: 3 months
Satisfaction of patients with the pharmacist's intervention, with a scale from 0 to 10
Time frame: 3 months after intervention
Changes in lifestyle related to asthma (free text field to complete by the patient)
Time frame: 3 months after intervention