Effect of Rabies Immunoglobulin on Immunogenicity of Post-exposure Rabies Vaccination in Obese Patients

Inclusion Criteria: 1. Male or female ages of \>= 18 years and older; 2. Experienced WHO category III rabies exposure excluding presenting wound at eye(s) or eye lid(s); 3. Either a) obese with BMI \>= 30 or b) normal weight and/or underweight with BMI \< 25; 4. Agree to independently consent to participate in all study procedures. Exclusion Criteria: 1. Positive skin test to ERIG or known hypersensitivity to ERIG or its excipients; 2. Co-enrolment with other studies or participated in other investigational drug studies or use of other investigational drugs within 4 weeks or five times the half-life of the investigational drug; 3. Female patients who are currently pregnant or breast feeding. 4. Presenting with wound at eye(s) or eye lid(s); 5. Receiving rabies vaccination more than 7 days for this exposure; 6. History of complete pre-exposure or post-exposure regimen with at least 3 doses; 7. Known of allergic to egg or poultry meat; 8. History of previous exposure to equine sera 9. Significant illness that might harm or increase the risk to the patients; 10. History of drug abuse or alcoholism.