The purpose of this study is to determine whether 18F-Al-NOTA-MATBBN is safety and effective for cancer diagnosis.
Observe radiation dose to healthy volunteers and patients; the correlation between integrin level and tumor/metastases uptake.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
DIAGNOSTIC
Masking
NONE
Enrollment
30
18F-Al-NOTA-MATBBN(PET imaging agent) given by vein before PET scans.Perform PET/CT for each enrolled volunteer or patient at 60-90min.
Imaging with 18F-Al-NOTA-MATBBN PET/CT.
Standardized uptake value of 18F-Al-NOTA-MATBBN in malignant lesions
The semiquantitative analysis will be performed by the same person for all the cases, and the standardized uptake value (SUV) of the tracer in malignant lesions will be measured.
Time frame: 1 day
Adverse events collection
Adverse events within 1 week after the injection and scanning of patients and patients will be followed and assessed.
Time frame: 1 week
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