Volumetric Bone Mineral Density and it's Relationship With Osteoporotic Fractures in Parkinson's Disease

Centre Hospitalier Régional d'Orléans90 enrolled

Overview

Idiopathic Parkinson's disease (IPD) is the second most frequent neurodegenerative disease. Its association with osteroporosis and fragility fracture is now clearly demonstrated, but the determinants of this osteoporosis are yet to be explained. Our aim was to study factors associated with volumetric bone mineral density (vBMD) and bone microstructure at the tibia and radius in IPD.

Study Type

INTERVENTIONAL

Allocation

Purpose

OTHER

Masking

NONE

Enrollment

Conditions

Idiopathic Parkinson's Disease

Interventions

High resolution peripheral scanner (HRpQCT).OTHER

radius and tibia osteodensitometry measurement

Eligibility

Sex: ALLMin age: 35 YearsMax age: 85 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients with idiopathic Parkinson's disease according to the criteria of the UKPDBB. * Parkinson's disease of moderate severity (Index HOEHN and Yahr \<5) * Patient can respond to questionnaires, with or without help Exclusion Criteria: * Patients with active psychiatric illness preventing the realization of examinations * Severe Parkinson's disease (Index HOEHN and Yahr ≥5 ) * Heavy-morbidity including heart failure NYHA\> 3 or chronic respiratory failure, terminal or severe renal impairment known dialyzed * Pregnancy

Locations (1)

CHR d'ORLEANS

Orléans, France

Outcomes

Primary Outcomes

Measurement of volumetric bone mineral density at the tibia and radius

Measurement performed by High Resolution peripheral Quantitative Computed Tomography (HRpQCT)

Time frame: 0 hour

Data from ClinicalTrials.gov

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