Serum Potassium Rate (PR) is a key indicator for medical management of patients with accidental hypothermia particularly for hypothermia related cardiac arrest (CA). Experts recommend a cut-off value for PR of 12 mmol/l for all hypothermic victims and 8 mmol/l for avalanche casualties. Any patient presenting a PR lower than the cut-off value should be considered for Extracorporeal Rewarming. This therapeutic strategy is vital for patient survival. However, there is no consensus about what type of vessels should be punctured in order to obtain an accurate potassium rate and what type of measurement technics should be used to measure this potassium rate. The investigators hypothesize that potassium rate in these patients will differ by 1 mmol/l in blood samples collected from a peripheral vein in contrast to a central vein. The investigators study is a prospective observational, multicentre study.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
DIAGNOSTIC
Masking
NONE
Enrollment
12
Patient in cardiac-arrest and cold exposure, diagnostic test: blood draw from three different vessels (central vein, artery, peripheral vein) and measuring of PR
University Hospital Vaudois
Lausanne, Valais, Switzerland
RECRUITINGHospital of Valais
Sion, Valais, Switzerland
RECRUITINGComparison of potassium rate in central venous blood and blood from a peripheral vein (measured in mmol/l)
Comparison of PR in central venous blood and blood from a peripheral vein (measured in mmol/l)
Time frame: 24 hours
Comparison of potassium rate in venous and arterial blood (measured in mmol/l)
Comparison of potassium rate in venous and arterial blood (measured in mmol/l)
Time frame: 24 hours
Comparison of potassium rate from laboratory analysis and at bedside via blood gas analyser (measured in mmol/l)
Comparison of potassium rate from laboratory analysis and at bedside via blood gas analyser (measured in mmol/l)
Time frame: 24 hours
Comparison of the time difference between laboratory analysis and blood gas analyzer at bed side (measured in minutes)
Comparison of the time difference between laboratory analysis and blood gas analyzer at bed side (measured in minutes)
Time frame: 24 hours
Survival and neurological outcome as measured by the Cerebral Performance Category Scale
Survival and neurological outcome as measured by the Cerebral Performance Category Scale
Time frame: 3 months
Study of biological parameters to calculate the Strong Ion Gap (measured in mEq/l) according to the Stewart Approach
1. For each sample, the apparent strong ion difference (SIDa) will be calculated as SIDa =(Na+ +K+ +Ca2+ +Mg2+)-(Cl- +Lac-) 2. The amount of weak plasma acid (A-) will be calculated as: A- = \[Alb\] × (0.123 × pH - 0.631) + \[PO4\] × (0.309 × pH - 0.469) 3. The effective strong ion difference (SIDe) will be calculated as: SIDe = 1000 × 2.46 × 10-11 × PaCO2/(10-pH) + \[A-\] To quantify unmeasured charges, the SIG will be calculated as: SIG = SIDa - SIDe
Time frame: 24 hours
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.