The purpose of this study is to investigate the effects of a Buteyko-based breathing technique on physiological and psychological parameters in adults with asthma
The investigators explore the effects of a Buteyko-based breathing technique training using a treatment group vs. control group design and a repeated measures design with follow-up measurements 3 and 6 months after the intervention. The sample size calculation was made for an effect of d = .20 with repeated measures, a power of 1- β = .80 and α = .05. Additionally the investigators plan to take measurements (only once) from healthy volunteers matching them (age and gender) with the asthma patients.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
63
Patients are trained in various exercises aiming at breath reduction and breath control as introduced by Dr. K. Buteyko
ARCIM Institute
Filderstadt, Baden-Wurttemberg, Germany
Change in Endtidal CO2
Capnometry
Time frame: Between baseline and 3 month follow up
Change in Nijmegen-Score
Questionnare assessing hyperventilation
Time frame: Between baseline and 3 month follow up
Change in Buteyko CP
Breath hold test
Time frame: Between baseline and 3 month follow up
Spirometry: FEV1
FEV1
Time frame: Between baseline and 3 month follow up
Spirometry: FEV1
FEV1
Time frame: Between baseline and 6 month follow up
Spirometry: FEV1/VCin
FEV1/VCin
Time frame: Between baseline and 3 month follow up
Spirometry: FEV1/VCin
FEV1/VCin
Time frame: Between baseline and 6 month follow up
Spirometry: PEF
PEF
Time frame: Between baseline and 3 month follow up
Spirometry: PEF
PEF
Time frame: Between baseline and 6 month follow up
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Oral exhaled Nitric oxide
Time frame: Between baseline and 3 month follow up
Oral exhaled Nitric oxide
Time frame: Between baseline and 6 month follow up
Heart Rate Variability (SDNN)
SDNN
Time frame: Between baseline and 3 month follow up
Heart Rate Variability (SDNN)
SDNN
Time frame: Between baseline and 6 month follow up
Heart Rate Variability (RMSSD)
RMSSD
Time frame: Between baseline and 3 month follow up
Heart Rate Variability (RMSSD)
RMSSD
Time frame: Between baseline and 6 month follow up
Heart Rate Variability (LF/HF)
LF/HF
Time frame: Between baseline and 3 month follow up
Heart Rate Variability (LF/HF)
LF/HF
Time frame: Between baseline and 6 month follow up
Vascular stiffness
Pulse Wave Velocity
Time frame: Between baseline and 3 month follow up
Vascular stiffness
Pulse Wave Velocity
Time frame: Between baseline and 6 month follow up
Blood Pressure
Systolic and Diastolic
Time frame: Between baseline and 3 month follow up
Blood Pressure
Systolic and Diastolic
Time frame: Between baseline and 6 month follow up
Haemodynamics Stroke volume
Stroke volume
Time frame: Between baseline and 3 month follow up
Haemodynamics Stroke volume
Stroke volume
Time frame: Between baseline and 6 month follow up
Haemodynamics Cardiac output
Cardiac output
Time frame: Between baseline and 3 month follow up
Haemodynamics Cardiac output
Cardiac output
Time frame: Between baseline and 6 month follow up
Haemodynamics Total Vascular Resistance
Total Vascular Resistance
Time frame: Between baseline and 3 month follow up
Haemodynamics Total Vascular Resistance
Total Vascular Resistance
Time frame: Between baseline and 6 month follow up
Haemodynamics Cardiac index
Cardiac index
Time frame: Between baseline and 3 month follow up
Haemodynamics Cardiac index
Cardiac index
Time frame: Between baseline and 6 month follow up
Haemodynamics Perfusion
Perfusion index
Time frame: Between baseline and 3 month follow up
Haemodynamics Perfusion
Perfusion index
Time frame: Between baseline and 6 month follow up
Haemodynamics Plethvariability
Plethvariability index (PVI)
Time frame: Between baseline and 3 month follow up
Haemodynamics Plethvariability
Plethvariability index (PVI)
Time frame: Between baseline and 6 month follow up
Oxygen Saturation
SpO2
Time frame: Between baseline and 3 month follow up
Oxygen Saturation
SpO2
Time frame: Between baseline and 6 month follow up
ACQ
Asthma Control Questionnaire, E. Juniper
Time frame: Between baseline and 3 month follow up
ACQ
Asthma Control Questionnaire, E. Juniper
Time frame: Between baseline and 6 month follow up
AQLQ
Asthma Quality of Life Questionnaire, E. Juniper
Time frame: Between baseline and 3 month follow up
AQLQ
Asthma Quality of Life Questionnaire, E. Juniper
Time frame: Between baseline and 6 month follow up
ARCIM Questionnaire
Questionnaire focusing on respiratory complaints like mucus, snoring, blocked nose.
Time frame: Between baseline and 3 month follow up
ARCIM Questionnaire
Questionnaire focusing on respiratory complaints like mucus, snoring, blocked nose.
Time frame: Between baseline and 6 month follow up
STAI Questionnaire
State and Trait Anxiety Inventory
Time frame: Between baseline and 3 month follow up
STAI Questionnaire
State and Trait Anxiety Inventory
Time frame: Between baseline and 6 month follow up
ASF Questionnaire
"Aachener Selbstwirksamkeitsfragebogen"
Time frame: Between baseline and 3 month follow up
ASF Questionnaire
"Aachener Selbstwirksamkeitsfragebogen"
Time frame: Between baseline and 6 month follow up
Asthma medication
Kind and dosage of asthma specific medication like steroids or betamimetics
Time frame: Between baseline and 3 month follow up
Asthma medication
Kind and dosage of asthma specific medication like steroids or betamimetics
Time frame: Between baseline and 6 month follow up