The purpose of the study is to testify the efficacy of treating abducens nerve palsy with ocular electroacupuncture or ocular acupuncture, and to compare the efficacy between these two interventions.
The purpose of the study is to testify whether ocular electroacupuncture or ocular acupuncture is effective for abducens nerve palsy (ANP), through treating ANP patient for 6 weeks, using self-invented acupoints according to anatomy of extraocular muscles innervated by abducens nerve, and using sham acupuncture as controlled group, and try to provide clinical evidence for promoting these new techniques.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
150
During intervention period, patients will continue to keep medications for primary condition. Patient's skin located in the extraocular muscles projection area is routinely disinfected. A diameter of 0.20 mm and length of 25 mm needle is inserted slowly. Piercing depth is about 20mm. The electropuncture apparatus is used, each group of electrodes are distinguished with different colors of wires to generate current stimulations of current 1.0\~1.5 milliampere (mA), voltage 9 volt(V), frequency 1.5 hertz (Hz), and duration of 40 minutes.
During intervention period, patients will continue to keep medications for primary condition. Patient's skin located in the extraocular muscles projection area is routinely disinfected. A diameter of 0.20 mm and length of 25 mm needle is inserted slowly. Piercing depth is about 20mm.The duration of intervention is 40 minutes.
The first affiliated hospital of Harbin Medical University
Harbin, Heilongjiang, China
RECRUITINGChange from Baseline in Ocular Motility Rating Score at 6 Weeks
The patient will receive grading of eyeball outward moving ability by investigator. The changes of rating score from baseline will be recorded.
Time frame: 6 week
Angle of diplopia deviation
Patients will receive computerized diplopia test with the guidance from an investigator. The data will be generated by the software automatically.
Time frame: 6 week
Eyeball movement distance
The distances of eyeball movement in outward direction will be measured. The differences between affected and healthy eye will be calculated.
Time frame: 6 week
The quality of life questionnaire for ocular motor nerve palsy
The patients will finish a questionnaire to evaluate their physical and psychological status during this trial.
Time frame: 6 week
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During intervention period, patients will continue to keep medications for primary condition. Patient's skin located in the extraocular muscles projection area is routinely disinfected. A diameter of 0.20 mm and length of 25 mm sham needle set is stick onto insertion area without piercing into the skin. The duration of intervention is 40 minutes.