Amino Acids Profiles in Premature Infants Receiving Nutritional Support

Xinhua Hospital, Shanghai Jiao Tong University School of Medicine124 enrolled

Overview

The aim of this study is to investigate the changes of amino acid metabolic profiles in different nutritional stages of preterm infants and determine the effects of nutritional intervention on the amino acid metabolic status of preterm infants.

Study Type

OBSERVATIONAL

Enrollment

124

Conditions

Premature Infant

Interventions

Collection of blood and urineOTHER

Collection of blood and urine before nutritional support, during total parenteral nutrition, during partial parenteral nutrition and during enteral nutrition

Eligibility

Sex: ALLHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: Premature infants, and admitted to hospital within 24 hours after birth; Documentation of informed consent; In need of receiving parenteral nutrition after birth; Exclusion Criteria: Premature infants with a parenteral nutrition period of less than 3 days; Inborn error of metabolism; Chromosomal abnormalities or multiple malformations;

Locations (1)

Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine

Shanghai, China

Outcomes

Primary Outcomes

Amino acid profiles in blood

Amino acid levels in blood

Time frame: through the transition to enteral nutrition, an average of 1 month

Secondary Outcomes

Weight

Time frame: Until the corrected gestational age is 37 weeks or discharged

Height

Time frame: Until the corrected gestational age is 37 weeks or discharged

Head circumference

Time frame: Until the corrected gestational age is 37 weeks or discharged

Data from ClinicalTrials.gov

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