Prediction of Dysplasia Within Sessile Serrated Polyps Using Endoscopic Imaging; a Prospective Observational Study

Western Sydney Local Health District86 enrolled

Overview

Study of endoscopic imaging in the detection of dysplasia within serrated colonic lesions \>= 8mm in size

Observational study Structured endoscopic imaging protocol devised Applied prospectively to sequential SSP \>= 8mm detected in a tertiary endoscopic resection cohort Review of specimens by blinded specialist pathologists Review of incongruent cases by endoscopists and pathologists

Study Type

OBSERVATIONAL

Enrollment

Conditions

Sessile Serrated Adenoma

Interventions

Endoscopic imagingDIAGNOSTIC_TEST

Analysis of the presence of dysplasia within sessile serrated polyps (SSP) using endoscopic imaging (high definition white light +- narrow band imaging)

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: * Patients referred to a tertiary endoscopic resection practice with any sessile serrated polyp (SSP) \>= 8mm Exclusion Criteria: * Patients referred to a tertiary endoscopic resection practice without sessile serrated polyps (SSP)

Locations (1)

Westmead Hospital

Westmead, New South Wales, Australia

Outcomes

Primary Outcomes

Dysplasia

Presence of dysplasia within sessile serrated polyps (SSP) using endoscopic imaging and congruence with histopathology

Time frame: at the initial procedure when the sessile serrated polyp (SSP) is analysed by the endoscopist compared with when the SSP is analysed at histopathology less than one week later. no ongoing determination

Secondary Outcomes

Sessile serrated polyp

Determination of a specific polyp as an sessile serrated polyp (SSP)

Time frame: at the initial procedure compared with histopathology within 1 week. no ongoing determination

Data from ClinicalTrials.gov

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