Retroperitoneal Ligation of Uterine Artery in Total Laparoscopic Hysterectomy for Enlarged Uterus

Kangbuk Samsung Hospital54 enrolled

Overview

This randomized trial is aimed to investigate the role of retroperitoneal TLH in enlarge uterus.

Laparoscopic hysterectomy is one of the most common gynecologic surgeries worldwide. Generally, in total laparoscopic hysterectomy (TLH), uterine arteries are coagulated or transected close to the uterus, alongside the cervix, like surgical technique of a conventional total abdominal hysterectomy. Recently, several studies showed that ligation of uterine artery where it originates from the internal iliac artery during TLH (so-called "retroperitoneal TLH") is effective for reducing blood loss. However, the application of this technique to clinical practice have not been well investigated in terms of its efficacy and safety. Moreover, most of the previous studies on retroperitoneal TLH were small case series or retrospective comparative studies with conventional TLH. Therefore, the investigators conducted this randomized trial to investigate the role of retroperitoneal TLH in enlarge uterus.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Hysterectomy

Interventions

Retroperitoneal liagation of uterine arteryPROCEDURE

the site of ligation of uterine artery is the area that it originates from the internal iliac artery during TLH

Classical ligation of uterine arteryPROCEDURE

the site of ligation of uterine artery is the area alongside the cervix

Eligibility

Sex: FEMALEMin age: 19 YearsMax age: 70 Years

Medical Language ↔ Plain English

Inclusion Criteria: * absence of pregnancy at the time of presentation * uterine volume between 12 and 18 weeks of gestation by pelvic examination * appropriate medical status for laparoscopic surgery (American Society of Anesthesiologists Physical Status classification 1 or 2) Exclusion Criteria: * any suggestion of malignant uterine or adnexal diseases * any major medical comorbidities or psychiatric illnesses, which could affect follow-up and/or compliance * an inability to understand and provide written informed consent.

Locations (1)

Kangbuk Samsung Hospital

Seoul, South Korea

Outcomes

Primary Outcomes

Operative blood loss

Operative blood loss was calculated by the anesthesiology unit as the difference between the total amount of suction and irrigation plus the difference between the total gauze weight before and after surgery.

Time frame: Operation day

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.