High Energy Phosphate Metabolites in Brain

Inclusion Criteria: * Men and women aged between 18-45 years * Healthy, based on the medical screening visit * Normal BMI for age (18.5-25.0 kg/m2) * Able to understand and to sign a written informed consent prior to trial entry * Informed consent signed Exclusion Criteria: * Known type 1 or type 2 diabetes, on anamnesis * Family history of type 2 diabetes (parents) * Any other metabolic disease possibly impacting the postprandial glucose and insulin response (on anamnesis, to the opinion of the medical expert) * Malabsorptive disorders including but not limited to pancreatitis, Crohn's disease, etc * Any history of neurological / psychological disease (meningitis, epilepsy), to the opinion of the investigator * Claustrophobia * Hearing disorders * Any medication impacting dietary fat absorption and metabolism like statins, bile acid sequestrants, lipid lowering medications, or fibrates , to the opinion of the medical expert * Pregnancy (on anamnesis) and/or lactation * Having any metallic, electronic, magnetic, or mechanical implants, devices, or objects, for safety reason linked to magnetic field exposure (MRS): * Aneurysm clip(s) * Cardiac pacemaker * Implanted cardioverter defibrillator (ICD) * Electronic implant or device * Magnetically-activated implant or device * Neurostimulation system * Spinal cord stimulator * Cochlear implant or implanted hearing aid * Insulin or infusion pump * Implanted drug infusion device * Any type of prosthesis or implant * Artificial or prosthetic limb * Any metallic fragment or foreign body * Hearing aid * Other implant * Subject injured by a metallic object or foreign body * History of cancer within the past year * Allergy or intolerance to any food or compound used * Currently following a strict exercise program (minimum three times per week) in order to either lose weight, gain muscle or reach competition standards for a chosen sport * Currently participating or having participated in a clinical trial during the past month * Subjects not willing and/or not able to comply with scheduled visits and the requirements of the research protocol. Subject having a hierarchical link with the investigator or co-investigators. * Subject who cannot be expected to comply with the research protocol.