Irrigating fluid absorbed during the endoscopic surgery may alter whole blood coagulation. However, little is known about the dose-response relationships of hemodilution. The investigators have therefore performed the present study to measure the effect of a mixture of 2.7% sorbitol-0.54% mannitol solution on the coagulation pathway according to the hemodilution level using a rotational thromboelastometry (ROTEM®) tests.
Study Type
OBSERVATIONAL
Enrollment
12
Venous blood was taken from 12 healthy volunteers and divided into four specimen bottles, which were diluted with different levels (0%, 10%, 20%, and 40%) using a mixture of 2.7% sorbitol-0.54% mannitol solution.
Seoul National University Bundang Hospital
Seongnam-si, Gyeonggi-do, South Korea
FIBTEM
Fibrinolytic pathway values of rotational thromboelastometry analysis/ FIBTEM is s a proper noun which means the status of fibrinolytic coagulation pathway.
Time frame: during the rotational thromboelastometry analysis/ an average of 1 hour
INTEM
Intrinsic pathway values of rotational thromboelastometry analysis/ INTEM is a proper noun which means the status of intrinsic coagulation pathway.
Time frame: during the rotational thromboelastometry analysis/ an average of 1 hour
EXTEM
Extrinsic pathway values of rotational thromboelastometry analysis/ EXTEM is a proper noun which means the status of extrinsic coagulation pathway.
Time frame: during the rotational thromboelastometry analysis/ an average of 1 hour
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