The study aims to investigate the effect of Permethrin 5% treatment on Signs and symptoms of Demodex-blepharitis in comparison to Synthomycine 5% and Fucithalmic (fusidic acid 1%) .
3 arms study. 75 patient total, 25 patients in each group. Group A (study group) patients will apply facially Permethrin 5% every night for 3 months. Group B patients will apply on the eyelids Fusidic acid 1% every night for 3 months. Group C patients will apply on the eyelids Synthomycine 5% every night for 3 months Follow up Evaluation will be made after one week, one month, two months, three months, 4 months and half a year.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
75
Facial skin application once a night for 3 months.
Eye ointment, eyelids and eyelashes application (chloramphenicol), once a night for 3 months.
viscous eye drops application once a night for 3 months.
Barzilai Medical Center
Ashkelon, Israel
Decrease in demodex infestation in group A (permethrin 5%).
significant decrease in demodex infestation in comparison to group B and C.
Time frame: 2 months
Improvement in symptoms and complaints in group A.
OSDI Questionnaires that describe the severity of the ocular surface disease condition are filled in each visit.
Time frame: 2 months
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.