To balance the oncological safety and cosmetic outcome is the basic principle of modern breast surgery. To preserve the nipple-areolar complex shows attractive cosmetic advantage but concerns regarding local recurrence make the oncological safety of nipple sparing mastectomy a controversial issue. Since the involvement of areolar pigmented skin by cancer is rare compared to that of nipple, we designed the current study to investigate the oncological safety and cosmetic outcome of Areola Sparing Mastectomy.
Primary breast cancer originated from areolae is rare. We hypothesized that nipple and areola are two separate anatomy tissue and have different oncological impact on the treatment of breast cancer. Areola Sparing Mastectomy (ASM) is a innovative procedure that involves of removal of nipple and preservation of areola the pigmented skin of which would improve the cosmetic outcome of mastectomy and lead to a illusion of congenital crater nipple in some patients.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
145
A small circular incision would be made to separate nipple from breast and an additional incision directly extended from nipple or located at other part of breast such as infra-mammary fold and subaxillary area would be made to remove the total mammary parenchyma. Routine implant based or flap base reconstruction would be performed subsequentially. Nipple reconstruction is optional.
Peking University People's Hospital
Beijing, Beijing Municipality, China
RECRUITINGRecurrence of areolar area
The frequency of histologically confirmed recurrence on the preserved pigmented areolar area.
Time frame: Five years after initial surgery
Cosmetic effect of reconstructed breast
The cosmetic results evaluated by a surgeon and a nurse through reviewing photographs.
Time frame: 2-4 weeks after surgery; 2 years and 5 years after surgery.
Adverse effect of surgery
Wound dehiscence, infection, suture exposure and extrusion.
Time frame: 4 weeks after surgery.
Disease free survival
Survival time to any recurrence and any cause death.
Time frame: 5 year after surgery
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