Evaluating the AMH Levels During Natural Cycle

ART Fertility Clinics LLC20 enrolled

Overview

To describe AMH serum levels dynamics during natural cycle using an automated assay.

The potential benefit would be using an automated assay for AMH, the dynamics of serum levels during the natural cycle and to check the inter-cycle variations. Because of the many clinical decisions that are based on AMH levels alone the results of this study could bring reassurance to the continuous use of AMH in daily practice. More importantly, no studies to date have been performed on the newer automated assays evaluating variability of AMH levels.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Anti-Mullerian Hormone Resistance

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 37 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Women with written informed consent. * Women between ≥ 18 and ≤ 37 years of age. * BMI between 18 and 28. * Normal physical examination and pelvic exam. Exclusion Criteria: * Pregnancy. * Breastfeeding. * History of any disease/iatrogenic intervention which could have had an impact on the ovarian reserve (e.g. ovarian surgery, chemotherapy, radiation of the pelvis, endometriosis) * Intake of OCP for the two last menstrual cycles.

Locations (1)

IVI Middle East Fertilty Clinic

Abu Dhabi, United Arab Emirates

Outcomes

Primary Outcomes

AMH serum levels dynamic

In order to describe each hormone and its dynamics, will determine mean and standard deviations in each time and it will be represented with boxplot figures. Moreover,the investigator will define polynomial interpolation for dynamic values and each hormone will be represented with mean polynomial interpolation and variance band

Time frame: 9months

Secondary Outcomes

Inter-cycle AMH variations

inter-cycle variability of AMH across two cycles is concluded independently that AMH varies a little between cycles.

Time frame: 9months

Data from ClinicalTrials.gov

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