Six Months Evaluation of Next Science Acne Creams on Facial Acne in Adult Females.

Inclusion Criteria: 1. Female ages 18 and above 2. Has 20 or more inflammatory lesions on the face (papules and pustules) as determined by qualified examiner at Start of Treatment. 3. In the area to be treated, has no significant facial dermatological conditions other than acne (as determined by the investigator) that would interfere with any study treatment or procedure 4. Is willing and able to discontinue use of all baseline acne treatments for the duration of their trial participation 5. Agrees to refrain from professional facial treatments during their trial participation. 6. Agrees to avoid tanning booth use and minimize sun exposure during their trial participation. 7. Is willing and able to follow instructions and procedures including attending scheduled study visits, which will require adequate transportation to the study site 8. Is able to read, understand and sign the informed consent document and communicate with study staff and investigator. Exclusion Criteria: 1. Has more than 2 nodules/cystic acne lesions on the face 2. Has a history of significant reactions to topical acne treatments, or a known allergy or hypersensitivity to any listed ingredients 3. Has any history of skin malignancy 4. Has used any systemic medications (including antibiotics, estrogens, retinoids) primarily for treatment of acne in the 21 days prior to randomization. 5. Has used estrogens primarily as treatment for acne in the 21 days prior to randomization (estrogens prescribed for other reasons will be allowed if stable for at least 30 days prior to randomization). 6. Has had any professional facial treatments in the 14 days prior to randomization. 7. Has received any investigational treatment in the 30 days prior to randomization. 8. Have any significant medical problems or other issues that would, in the investigator's judgment, affect their suitability for participation in this trial.