Pilot Study of Probiotics in Pre-diabetic Adolescents

Inclusion Criteria: * Male or female, 13-19 y. of age at Visit 1. * BMI: 99th percentile or greater * Acanthosis nigricans * Pubertal Tanner stage ≥3 Exclusion Criteria: * Secondary diabetes (i.e. post-transplant diabetes mellitus (DM) or cystic fibrosis DM), monogenic forms of diabetes (i.e. MODY), autoimmune diabetes or presence of islet autoantibodies. * Known severe immunodeficiency, or immune compromised. * Current or previous history for insulin or metformin therapy (within last 3 months). * Antibiotic or probiotic therapy 3 months prior to enrollment. * Start of new dietary intervention within 1 month prior to enrollment. * Diagnosed food hypersensitivity or active gastrointestinal disease