Evaluating the Efficacy and Compatibility of Efinaconazole 10% Solution (Jublia) for the Treatment of Toenail Onychomycosis in Patients Wearing Toenail Polish Compared to Those Without Polish

Inclusion Criteria: * Female age 19-70, as 19 is the legal age in Alabama * DLSO affecting at least 1 great toenail diagnosed with positive potassium hydroxide microscopy and culture of a dermatophyte * Suitable for application of topical antifungal therapy, in the opinion of the investigator * Target toenail thickness of 3 mm or less as measured by digital caliper, as thickness greater than 3 mm may allow inclusion of patient with severe onychomycosis, and this was the criteria used in the pivotal trial using topical efinaconazole for onychomycosis * Women of childbearing potential will be required to use birth control and a negative urine pregnancy test must be documented prior to initiating treatment Exclusion Criteria: * History of immunosuppression or concurrent use of immunosuppressant drugs * History of uncontrolled diabetes mellitus * History of psoriasis or any other condition that might interfere with the toenail evaluation * Three or more dermatophytomas (streaks) on the target nail * Severe DLSO of the target nail * Patients who cannot refrain from wearing gel or plastic based polishes that are used in salons and that require curing