The goal is this study is to evaluate how the skin surface lipid composition is correlated with overall sebum production, barrier function, and inflammatory disease status. We hypothesize that there will be differences in the skin surface composition among subjects of various groups: 1. Young vs older healthy population 2. Atopic dermatitis vs Acne vs Healthy controls 3. Active smokers vs non-smoker controls
This study will be conducted through the use of painless tapes to collect lipid. These will be applied to the skin and removed. Secondly, the barrier function will be evaluated through the use of non-invasive painless devices that measure sebum, skin water loss, and skin hydration.
Study Type
OBSERVATIONAL
Enrollment
41
All five groups will undergo the same study intervention: skin surface lipid collection via tapes and skin barrier function evaluated with non-invasive painless devices.
UC Davis Department of Dermatology
Sacramento, California, United States
Lipid Profile-aging
The lipid profile of the subject group will be evaluated through the use of painless tapes that will be applied to the skin.
Time frame: 1 day
Lipid Profile-acne
The lipid profile of the subject group will be evaluated through the use of painless tapes that will be applied to the skin.
Time frame: 1 day
Lipid Profile-atopic dermatitis
The lipid profile of the subject group will be evaluated through the use of painless tapes that will be applied to the skin.
Time frame: 1 day
Lipid Profile-smoking
The lipid profile of the subject group will be evaluated through the use of painless tapes that will be applied to the skin.
Time frame: 1 day
Skin Barrier Function- aging
The skin barrier function will be evaluated for this group through the use of non-invasive handheld devices. These devices provide information about sebum secretion rate, skin water loss, and skin hydration.
Time frame: 1 day
Skin Barrier Function- acne
The skin barrier function will be evaluated for this group through the use of non-invasive handheld devices. These devices provide information about sebum secretion rate, skin water loss, and skin hydration.
Time frame: 1 day
Skin Barrier Function- atopic dermatitis
The skin barrier function will be evaluated for this group through the use of non-invasive handheld devices. These devices provide information about sebum secretion rate, skin water loss, and skin hydration.
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Time frame: 1 day
Skin Barrier Function- smoking
The skin barrier function will be evaluated for this group through the use of non-invasive handheld devices. These devices provide information about sebum secretion rate, skin water loss, and skin hydration.
Time frame: 1 day