Mobilisation following knee arthroplasty is an important aspect to achieve early and enhanced recovery after surgery and sufficient joint function. Analgesia is a crucial therapeutic element in this context. This RCT evaluates two analgetic regimens for patients undergoing primary total knee-replacement to assess impact on postoperative recovery.
Mobilisation following knee arthroplasty is important for patients to achieve early and enhanced recovery after surgery and sufficient joint function. Analgesia is a crucial therapeutic element in this context. There is evidence that regional- anaesthesiological catheter techniques are very efficient to control pain postoperatively. On the other hand, motoric function may be reduced due to nerve blocks depending on location and concentration of drug used. Local infiltration of the knee during surgery is an alternative component in pain management that may reduce impaired motor function and allow early mobilisation of patients. However, currently it is not known which analgesia technique provides optimal pain control paralleled with sufficient motor function. Against this background, this RCT evaluates two analgesia regimens for patients undergoing primary total knee-replacement to assess impact on postoperative recovery.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
40
Patient receive an infiltration of local anaesthetics around the knee directly after total knee replacement for postoperative pain control.
Patients receive a single shot nerve block of the proximal Nervus ischiadicus and a catheter placed closed to the Nervus saphenus for perioperative pain control using ultrasound guided techniques.
Charité University Berlin (CCM)
Berlin, Germany
time to first mobilisation (standing)
time from end of surgery until patients is able to stand
Time frame: up to 48h postoperatively
patients satisfaction (11-point likert scale)
global satisfaction of patients
Time frame: up to 7 days postoperatively
time to first mobilisation (walking)
time from end of surgery until patients is able to walk
Time frame: up to 7 days postoperatively
complications
complications during perioperative care process (e.g. thrombosis, re-operation, infection)
Time frame: up to 7 days postoperatively
time to achieve full joint mobility
time to achieve full joint mobility (0/0/90°)
Time frame: up to 7 days postoperatively
pain intensity of patients (11-point likert visual analogue scale) measured 3 times daily (mean)
mean pain intensity of patients
Time frame: up to 7 days postoperatively
rescue pain medication
number of patients requiring rescue pain medication
Time frame: up to 7 days postoperatively
pain medication perioperatively
pain medication perioperatively (e.g. NSAIDs, opioids, con-analgetics)
Time frame: up to 7 days postoperatively
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time to discharge
time to discharge from hospital
Time frame: up to 14 days postoperatively