Frozen-thawed Embryo Transfer in a Natural Cycle: hCG Triggering Versus LH Home Test

Phase 4TerminatedNCT03115320

Tampere University Hospital62 enrolled

Overview

The primary aim of this study is to find out if ovulation triggered with hCG provides any additional benefit in comparison to spontaneous LH surge measured with the LH surge home test when transferring frozen-thawed embryo in a natural cycle.

The aim of this study is to find out the best method for the ovulation triggering. We study the live birth rates in the both groups.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Infertility

Interventions

Human chorionic gonadotropinDRUG

Human chorionic gonadotropin (Pregnyl, 5000IU) is used in the medication group to confirme the ovulation.

Home ovulation testOTHER

The ovulation in the natural menstrual cycle is confirmed by the home ovulation tests from the urine.

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 42 Years

Medical Language ↔ Plain English

Inclusion Criteria: * \- Patient with IVF or ICSI cycle and therefore having frozen-thawed embryos * Regular menstruation cycle * Patient's willingness to participate in the study Exclusion Criteria: * \- Irregular menstrual cycle demanding preparing endometrium with hormones for frozen-thawed embryo * No frozen embryos after IVF cycle * Allergy to Pregnyl® or some of its ingredients in the medication or other contraindications due to Pregnyl®

Locations (1)

Tampere University Hospital

Tampere, Finland

Outcomes

Primary Outcomes

Live birth rate

Time frame: At possible delivery (about 40 weeks)

Secondary Outcomes

Ongoing pregnancy rate

Time frame: After two weeks

Data from ClinicalTrials.gov

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