Testosterone Replacement in Postmenopausal Women With Stress Urinary Incontinence

Inclusion Criteria: * Inclusion Criteria: * Ambulatory, postmenopausal women * The presence of stress urinary incontinence, defined as involuntary urine loss during physical activity, cough, or sneeze. * Able to understand and give informed consent. * Those on estrogen replacement therapy prior to the study should have been on a stable regimen for at least three months. For those who are not on estrogen replacement therapy prior to the study, will not be started on estrogen for the duration of the study. * Normal Pap smear and mammogram in the preceding 12 months by history and chart review. Exclusion Criteria: * Uncontrolled depression as assessed by history and physical exam. * Those with any acute or chronic illness, malignant disease, fever of known or unknown origin, diabetes mellitus (fasting blood glucose \> 126 mg/dl), or uncontrolled hypertension (defined as blood pressure greater than 160/100). * Current urinary tract infection (UTI). For those with acute UTI, treatment will be given and repeat culture should be negative before enrollment. * Severe obesity defined as body mass index of greater than 40 kg/m2. * Current or recent (last 6 months) use of illicit drugs (which may affect appetite, food intake, metabolism, and/or compliance with the protocol). * Current or recent (last 6 months) alcohol or drug dependence. * Significant liver function abnormalities defined as AST, ALT, or alkaline phosphatase value of greater than three times the upper limit of normal in our Clinical Pathology Laboratory, or serum bilirubin levels of greater than 2 mg/dl. * History of breast or endometrial cancer. * History of hyperandrogenic disorders such as hirsutism and polycystic ovary disease. * Previous intolerance to testosterone. * Women with abnormal PAP smears or mammograms will be included only after they have been evaluated by their gynecologists and breast and uterine/cervical cancers have been excluded by appropriate diagnostic tests. * Women with significant dementia as assessed by history and physical exam. * Those with disabilities that would prevent them from participating in the outcome testing, including tests of pelvic floor strength (e.g. severe arthritis, Parkinson's disease, stroke, or myopathy). * Those who have received in the preceding three months drugs known to affect testosterone production or metabolism such as Ketoconazole, Megace, and or anabolic/androgenic steroids. * Because of their age and post-menopausal status, spontaneous pregnancy is unlikely. Regardless, women who are pregnant, seeking to become pregnant in the next six months, or breastfeeding will not be included. * Subjects who cannot have an MRI due to metal implants or pacemaker.