Concordance of Inivata Liquid Biopsy With Standard Tissue Biopsy

Inclusion Criteria: * Written, signed and dated informed consent * Male \& female patients aged 18 years and over diagnosed with stage IIIb/IV non-squamous NSCLC. * Patients intended to initiate first-line treatment (Arms A and B) * Patients who plan to have or have had a recent tumor tissue biopsy taken as part of their standard of care (Arm A) * Patient must understand and be able, willing and likely to fully comply with all study procedures and restrictions. Exclusion Criteria: * Patients who have received any approved or experimental cancer therapy since their most recent NSCLC tissue biopsy * Any history of metastatic cancer. * Previous malignancy in the last 2 years (except basal cell carcinoma of the skin or pre-invasive carcinoma of the cervix). * Patient with a severe acute or chronic medical or psychiatric condition or laboratory abnormality