The purpose of this study is to determine the effects of diet type selection based on response to a Carbohydrate Intolerance Questionnaire (CIQ) and genetic screening on success to a weight loss and exercise program.
The purpose of this study is to determine if stratification of individuals based on responses to a Carbohydrate Intolerance Questionnaire (CIQ), genetic screening, and/or DNA methylation affects weight loss success and/or health outcomes of women following the Curves moderate carbohydrate, high protein, low fat diet (30% carbohydrate, 45% protein, 25% fat) or the Curves carbohydrate restricted, high protein, moderate fat diet (20% carbohydrate, 45% protein, 35% fat).
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE
Enrollment
51
Positive Carbohydrate Intolerance Questionnaire plus High Carbohydrate Diet
Positive Carbohydrate Intolerance Questionnaire plus High Protein Diet
Negative Carbohydrate Intolerance Questionnaire plus High Carbohydrate Diet
Effects of diet selection on physical activity patterns changes (steps per day)
Time frame: 24 weeks
Effects of diet selection on body weight changes (pounds)
Time frame: 24 weeks
Effects of diet selection on hip/waist ratio changes (inches)
Time frame: 24 weeks
Effects of diet selection on Resting Energy Expenditure (REE) changes (calories per day)
Time frame: 24 weeks
Effects of diet selection on Blood Pressure (BP) changes (mmHG)
Time frame: 24 weeks
Effects of diet selection on Heart Rate (HR) changes (beats per minute)
Time frame: 24 weeks
Effects of diet selection on body composition (DXA) changes (percent fat mass)
Time frame: 24 weeks
Effects of diet selection on Bioelectrical Impedance Analysis (BIA) changes (flow impedance)
Time frame: 24 weeks
Effects of diet selection on a chemistry-15 blood panel changes
Time frame: 24 weeks
Effects of diet selection on a cell blood count (CBC) blood panel changes
Time frame: 24 weeks
Effects of diet selection on lipid panel changes
Time frame: 24 weeks
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Negative Carbohydrate Intolerance Questionnaire plus High Protein Diet
Effects of diet selection on maximal cardiopulmonary capacity changes (ml/kg/min)
Time frame: 24 weeks
Effects of diet selection on muscular strength through a 1 repetition maximum (1 RM) test
Time frame: 24 weeks
Effects of diet selection on muscular endurance through a maximal repetition test
Time frame: 24 weeks
Effects of diet selection on gene expression changes
Time frame: 24 weeks
Effects of diet selection on DNA methylation changes
Time frame: 24 weeks