Electronic Chromoendoscopy for Polyp Characterization

N/ACompletedNCT03118856

University of Erlangen-Nürnberg Medical School230 enrolled

Overview

To assess the accuracy of predicting histology of colorectal polyps with electronic chromoendoscopy.

Study Type

OBSERVATIONAL

Enrollment

230

Conditions

Colorectal Polyp

Interventions

Prediction of HistologyDIAGNOSTIC_TEST

The accuracy of predicting the histology of colorectal polyps will be assessed with HD-WLE and EC

Eligibility

Sex: ALLMin age: 18 YearsMax age: 90 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * patients undergoing screening or surveillance colonoscopy * written informed consent Exclusion Criteria: * inadequate bowel preparation * polyposis syndromes * history of colectomy * use of anticoagulants

Locations (1)

University Hospital Erlangen

Erlangen, Germany

Outcomes

Primary Outcomes

Accuracy of predicting histology with EC

Polyps will be visualized in white-light and the location and size will be noted. Afterwards, electronic chromoendoscopy will be used to visualize and enhance the mucosal vascular pattern and the mucosal surface pattern morphology of the polyp. The endoscopist will then make a real time assessment of each polyp according to size, shape, Paris classification and surface characteristics including pit pattern and mucosal vascular pattern morphology, colour, and type of depression. Further, a level of confidence (high or low) will be made for the real time histology prediction. Finally, all polyps will be removed using standard techniques and processed for pathological evaluation and real time and histological results will be compared.

Time frame: 1 year

Data from ClinicalTrials.gov

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