Oxytocin's Effect on Social Pain Empathy

N/AUnknownNCT03122067

University of Electronic Science and Technology of China60 enrolled

Overview

The aim of the present experiment is to examine oxytocin's behavioral and neural effects on social pain empathy

In the current study, the investigators plan to examine whether oxytocin modulates behavior and neural activity during observing another person being excluded in an online ball-tossing game (a modified cyberball paradigm).

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

DOUBLE

Enrollment

Conditions

Healthy

Interventions

oxytocin treatmentDRUG

intranasal administration of oxytocin

placebo treatmentDRUG

intranasal administration of placebo

Eligibility

Sex: MALEMin age: 18 YearsMax age: 30 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * healthy participants without past or current psychiatric or neurological disorders Exclusion Criteria: * history of head injury * medical or psychiatric illness * smoking or drinking 24 hours before experiment

Locations (1)

School of Life Science and Technology, University of Electronic Science and Technology of China

Chengdu, Sichuan, China

RECRUITING

Outcomes

Primary Outcomes

Neural activity changes associated with oxytocin administration

fMRI-assessed brain activity during observing other being socially excluded

Time frame: 45-60 minutes after drug administration

Secondary Outcomes

Behavioral changes associated with oxytocin administration: ball-tossing

Number of tosses to the other players (the excluder, new player, or previously excluded player)

Time frame: 45-60 minutes after drug administration

Central Contacts

Keith Kendrick, Dr.

CONTACT

k.kendrick.uestc@gmail.com

Data from ClinicalTrials.gov

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