Study of the Relation Between Lipid Myocardial Overload Evaluated by Cardiac Magnetic Resonance Imaging (MRI), Alteration of Longitudinal Myocardial Deformations by Echocardiography, and Clinical Achievements (Functional, Biological and Electrical) in Fabry Disease, and Its Outcomes.

Inclusion Criteria: Patients group : * Adults (age ≥18 years), male and female. * Patients diagnosed genetically having Fabry disease, with or without clinical cardiac symptoms and with different evolution stades of the disease. * For female in age of procreation, efficient contraception will be required and a negative pregnancy test. * Oral agreement of the patient after having read information note. * Patient affiliated to social national Security registry. Healthy volunteers group: * Adults (age ≥18 years), male and female. * Unscathed of cardiovascular pathologies and cardiovascular risk factors. * For female in age of procreation, efficient contraception will be required and a negative pregnancy test. * Oral agreement of the patient after having read information note. * Patient affiliated to social national Security registry. Exclusion Criteria: For the 2 groups : * Extracardiac pathology limiting life expectancy \<1 year (cancer). * Pregnant or breastfeeding female. * Claustrophobia. * Mechanical prosthetic valve. * Severe obesity \> 140 kg * Patients with intracardiac device (implantable cardiac defibrillator, pace maker, resynchronisation), surgical clips not MRI compatible, neurosensorial stimulators, cochlear implants, ferromagnetic foreign bodies (ocular, cerebral), neurosurgical derivation valves) * Impossibility to provide consent or refusal to sign the consent form. For the patients: \- Previous history of hypersensitivity to gadolinium.