A Pilot Study of Hemoporfin PDT in Children With Port-wine Stain

Inclusion Criteria: * Children with clinical diagnosis of PWS； * Age range: 7 to 14 years-old； * Voluntarily participated and Written informed consent signed Exclusion Criteria: * Therapy area located outside of head and neck; * Other skin diseases that might interfere with the efficacy evaluation; * Therapy area was previously received isotope or PDT or other treatment which might interfere with the efficacy evaluation; * Allergy to porphyrins and analogues; Photosensitivity; Porphyria; Allergic constitution; * Scar diathesis; * Immunocompromised conditions; * Electrocardiographic abnormalities or organic heart diseases; * Coagulation disorders; * Hepatic or renal functions abnormal (alanine aminotransferase or aspartate transaminase or total bilirubin \> 1.5 upper limit of normal \[ULN\], or serum creatinine or blood urea nitrogen \> 1.5 ULN); * Psychiatric diseases; Severe endocrinopathies; * Previous therapy of PWS within the last 4 weeks; * Participation in any clinical studies within the last 4 weeks; * Be judged not suitable to participate the study by the investigators