The Effect of Vocal Rest Versus Vocalization Following Xeomin® Injections in Spasmodic Dysphonia

London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's20 enrolled

Overview

This study will compare the effects of vocal rest versus continuous vocalization for one hour immediately following botulinum toxin injections for adductor spasmodic dysphonia.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Adductor Spasmodic Dysphonia

Interventions

Vocal rest versus vocalizationBEHAVIORAL

A comparison of one hour of vocal rest versus continuous vocalization after botulinum toxin injection

Eligibility

Sex: ALLMin age: 21 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Diagnosed with adductor spasmodic dysphonia (ADSD) by an experienced neurologist and otolaryngologist. ADSD patients who have been stabilized on their treatment dose for at least 2 treatment cycles. Exclusion Criteria: * Diagnosed with another neurological disorder that is combined with ADSD (i.e. Parkinson's disease and ADSD). Previous history of an additional vocal pathology (i.e. vocal polps, vocal nodules, unilateral vocal fold paralysis, etc.)

Locations (1)

LawsonHRI

London, Ontario, Canada

Outcomes

Primary Outcomes

Severity of spasmodic dysphonia symptoms

Acoustic measures and perceptual ratings of vocal spasm severity

Time frame: Six weeks post-treatment

Patient-reported outcome measures of symptoms and communication

Six patient-reported questionnaires related to symptoms, communication effectiveness, quality of life, and self-efficacy

Time frame: six weeks post-treatment

Data from ClinicalTrials.gov

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