This study evaluated the predictive value of β2-microspheres for postoperative delirium (POD) in the elderly after orthopedic surgery. For this purpose, the levels of β2-microspheres in plasma and cerebrospinal fluid were compared between the POD and non-POD groups.
In this study, plasma and cerebrospinal fluid of the patients were collected to detect the levels of β2-microspheres before operation. Also, the patients were interviewed one day before the surgery and on postoperative days 1-3 by the Confusion Assessment Method and then divided them into POD and non-POD groups. The aim of the present study was to assess whether higher levels of β2-microspheres could predict the occurrence of POD.
Study Type
OBSERVATIONAL
Enrollment
184
Zhongda Hospital
Nanjing, Jiangsu, China
The incidence of POD
The patients were interviewed one day before the surgery and on postoperative days 1-3 by the Confusion Assessment Method and then divided them into POD and non-POD groups.
Time frame: 4 days
The levels of β2-microspheres in plasma and cerebrospinal fluid
Before surgery, plasma and cerebrospinal fluid of the patients were collected to detect the levels of β2-microspheres.
Time frame: 1 day
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