The trial evaluates the safety and efficacy of the olfactory mucosa-derived mesenchymal stem cells based therapy for the patients with chronic laryngeal and tracheal stenosis
Trial evaluating the safety and efficacy of olfactory mucosa-derived mesenchymal stem cells based therapy for the patients with chronic laryngeal and tracheal stenosis. Mesenchymal stem cells are obtained from tissue biopsy of olfactory mucosa using explant method. Biomass of autologous mesenchymal stem cells in 10% human albumin solution is injected submucosally around and over the tissue after removal of a granuloma tissue during surgical intervention.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
12
Olfactory mucosa-derived mesenchymal stem cells
The Republican Center for Research and Practice in Otolaryngology
Minsk, Belarus
The Republican Research and Practical Center for Epidemiology and Microbiology
Minsk, Belarus
Number of patients who didn't require the repeated surgical interventions
Time frame: 1 year
Tracheostomy decannulation
Removal of the tracheostomy tube after the treatment.
Time frame: 6 month
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.