This is an observational, retrospective, non-interventional study that will include schizophrenic patients who were initiated on AOM treatment during an schizophrenia-related hospitalisation at least 6 months before data collection and in a real clinical practice setting.
This is an observational, retrospective, non-interventional study that will include schizophrenic patients who were initiated on AOM treatment during an schizophrenia-related hospitalisation at least 6 months before data collection and in a real clinical practice setting. Data from each patient will be collected after informed consent is obtained (if possible), and will include retrospective information mainly from the index date (start of AOM treatment, baseline timepoint) until the last information available in the patient file at the time of data collection (minimum of 6 months after the index date). Data will be retrospectively collected from all visits occurring as per clinical practice (usually once-monthly).
Study Type
OBSERVATIONAL
Enrollment
119
Hospital Universitario de Álava
Alava, Spain
Hospital Fundación Alcorcón
Alcorcón, Spain
Numància Salut Mental (Parc Sanitari St Joan de Deu)
Barcelona, Spain
Persistence (days) with aripiprazole once-monthly
To describe in real-world practice the impact of demographic and clinical characteristics on persistence in patients with schizophrenia initiated on aripiprazole once-monthly (AOM) during an inpatient stay due to an acute schizophrenia relapse.
Time frame: First 6 months after treatment initiation
Description of reasons of treatment discontinuation (number of discontinuations per reason)
Date of AOM interruption or discontinuation and reason for discontinuation
Time frame: From treatment initiation up to patient inclusion (minimum 6 months)
Change over time in Clinical Global Impressions - Severity (CGI-S) scale
Clinical Global Impressions - Severity (CGI-S) scale at index date (if available in patient's file or estimated by the investigator according to medical records) and CGI-S up to patient's inclusion (if available in patients' file or estimated by the investigator according to medical records). CGI-S up to patient's inclusion (if available in patients' file or estimated by the investigator according to medical records).
Time frame: From treatment initiation up to patient inclusion (minimum 6 months)
Change over time in the Brief Psychiatric Rating Scale (BPRS)
Brief Psychiatric Rating Scale (BPRS) at index date (if available in patient's file) and BPRS up to the patient's inclusion (if available in patients' file).
Time frame: From treatment initiation up to patient inclusion (minimum 6 months)
Description of AOM treatment (starting dose and dose adjustments, number of injections, prior and concomitant medications, settings)
Description of AOM treatment (starting dose and dose adjustments, number of injections, prior and concomitant medications, settings)
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Hospital de Ciudad Real
Ciudad Real, Spain
Hospital IAS Girona
Girona, Spain
Hospital Universitari Bellvitge
L'Hospitalet de Llobregat, Spain
Complejo Asistencial Universitario de Leon
León, Spain
Fundación Jiménez Díaz
Madrid, Spain
HGU Gregorio Marañón
Madrid, Spain
Hospital Infanta Leonor
Madrid, Spain
...and 5 more locations
Time frame: From treatment initiation up to patient inclusion (minimum 6 months)
Description of health resource use (HRU) related to schizophrenia (hospitalisations, medications, non-pharmacological therapies, outpatient visits, procedures)
Description of health resource use (HRU) related to schizophrenia (hospitalisations, medications, non-pharmacological therapies, outpatient visits, procedures)
Time frame: From treatment initiation up to patient inclusion (minimum 6 months)
Description of non-pharmacological interventions aiming to improve functionality (types, numbers of patients per type)
Description of non-pharmacological interventions aiming to improve functionality (including, if applicable, initiation and end dates of Institutional support, Cognitive behavioural therapy (CBT), Assertive Community Treatment/Case management, Group or individual psychoeducation, Family psychoeducation, Group or individual psychotherapy, Structured rehabilitation program, Occupational support, Severe mental illness management program)
Time frame: From treatment initiation up to patient inclusion (minimum 6 months)
Description of patterns of alcohol and drug abuse and/or dependence (patterns of drug abuse, type of substance, frequency of consumption)
To qualitatively describe patterns of drug abuse and/or dependence
Time frame: From treatment initiation up to patient inclusion (minimum 6 months)