Etiology of Motor Developmental Delay in Children

Bundang CHA Hospital1,355 enrolled

Overview

This study aims to identify the etiology of children with motor developmental delay, in association with the results of magnetic resonance imaging and genetic analysis.

Results of other available assessments including Gross Motor Function Measurements and Bayley Scale of Infant Development, second edition, modified Ashworth Scale, IQ score and developmental language assessments are to be collected.

Study Type

OBSERVATIONAL

Enrollment

1,355

Conditions

Delayed;Development;Physical Delayed; Development, Intellectual

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: * clinical diagnosis of motor developmental delay * available results of functional assessments at ages older than 18 months Functional measures include either GMFM or BSID\_II Exclusion Criteria: * single domain delay other than motor (e.g., speech delay)

Outcomes

Primary Outcomes

Change of Gross Motor Function Classification System from baseline at 6 months

To avoid variation in each individual the exact date of evaluation for every outcome is included to estimate the exact time from birth

Time frame: through study completion, an average of 1 year

Secondary Outcomes

Brain MRI findings

the first brain MRI taken after the event causative to developmental delay, read by radiology specialists

Time frame: From the date of the first documented developmental delay until the date of last documentation or date of death from any cause, whichever came first, assessed up to 100 months

Mental quotient

BSID-II mental month estimated/actual age in month times 100

Time frame: From the date of the first documented developmental delay until the date of last documentation or date of death from any cause, whichever came first, assessed up to 100 months

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.