Pulmonary hypertension is high blood pressure in the arteries to the lungs. It is a serious condition. It causes the blood vessels that carry blood from the heart to the lungs to become hard and narrow. When this happens, the heart has to work harder to pump the blood through. Some babies are born with pulmonary hypertension (PH). Doctors might use INOmax (a gas the baby breathes) to help newborn babies (neonates) with PH. This study will use information from the records of registered babies to see how effective and safe INOmax is for treating premature and other newborn babies for up to 11 days after they are born.
Study Type
OBSERVATIONAL
Enrollment
140
Nitric oxide gas for inhalation provided via mechanical ventilation or non invasive ventilation
Number of neonates with significant response to INOmax treatment within each age group
Significant response is defined as at least a 25% improvement from baseline in oxygenation index or surrogate oxygenation index (OI/SOI) during INOMAX treatment
Time frame: within 108 hours
Number of neonates with significant response to Inomax treatment within each age group and severity group
The severity of pulmonary hypertension (PH) is classified for each participant Categories: Mild, Moderate, Severe
Time frame: within 108 hours
Time to reach significant response to Inomax treatment within each age group and severity group
The median time to INOmax complete response (25% improvement) for neonates with each baseline PH severity classification Categories: Mild, Moderate, Severe
Time frame: within 108 hours
Number of neonates with partial response to INOmax treatment within each age group and severity group
Partial response is defined as less than a 25% improvement in OI/SOI during INOmax treatment
Time frame: within 108 hours
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
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