Resting Metabolic Rate, Fat Distribution, Endocrine and Metabolic Features in Polycystic Ovary Syndrome

Fondazione Policlinico Universitario Agostino Gemelli IRCCS160 enrolled

Overview

In a longitudinal, prospective and observational study, patients with PCOS and controls wore the SenseWear Armband for 2 days. Resting metabolic rati (kcal/die), total energy expenditure (MET, kcal) were evaluated. Ultrasonographic pelvic examinations, hirsutism score, anthropometric and menstrual pattern evaluation, hormonal profile assays, oral glucose tolerance test (OGTT) and lipid profile were performed.

Study Type

OBSERVATIONAL

Enrollment

160

Conditions

Polycystic Ovary Syndrome

Interventions

SenseWear Armband (SWA) monitoringDIAGNOSTIC_TEST

Participants wore the SWA on their right arm

total body dual-energy X-ray absorptiometryDIAGNOSTIC_TEST

DEXA was used to estimate abdominal visceral adipose tissue and subcutaneous adipose tissue

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 40 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * . PCOS diagnosed according with the Rotterdam Consensus Conference criteria Exclusion Criteria: * presence of a late-onset adrenal enzyme defect * Significant liver or renal impairment * pregnancy and nursing * neoplasm * cardiovascular disease * other hormonal dysfunctions

Outcomes

Primary Outcomes

differences in resting metabolic rate

Time frame: 2 days

Secondary Outcomes

differences in body fat distribution

Time frame: 1 day

Data from ClinicalTrials.gov

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