This study evaluates the effects of a prescribed 4-week raw, plant-based dietary intervention in the treatment of excess body weight, hypercholesterolemia, and hypertension in the clinical setting.
Plant-based diets have emerged in the literature as effective therapeutic strategies in the reduction of body weight, serum lipids and blood pressure. In addition, raw fruit and vegetable consumption has also been associated with the reduction of these clinical indicators. Participants were instructed to follow a prescribed, raw, plant-based dietary intervention for four weeks. All animal products, including eggs and dairy, were excluded. Cooked foods, free oils, soda, alcohol and coffee were also to be excluded. All meals and snacks were provided to the participants for the full duration of the intervention. Emphasized were raw fruits and vegetables, while seeds, avocado, raw oats, raw buckwheat, and dehydrated foods were prepared as condiments. Vitamin, herbal, and mineral supplements were to be discontinued unless otherwise clinically indicated. Participants were not advised to alter their exercise habits. Participants came to a total of 4 follow-up visits. A laboratory panel was obtained at baseline and at 4-weeks. A 24-hour recall was also conducted at baseline and at 4-weeks. Anthropometrics, hemodynamics, and medication needs were assessed on a weekly basis.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
33
Subjects consumed a raw, vegan diet for 4-weeks with an emphasis on raw fruit and vegetable consumption.
Montgomery Heart & Wellness
Houston, Texas, United States
Change in body weight
Weight (kg) was documented at baseline and during 4 additional weekly follow-up visits
Time frame: Baseline, follow-up weeks 1-4
Change in serum low-density lipoprotein cholesterol (LDL)
LDL cholesterol (mg/dL) was documented at baseline and after 4-weeks
Time frame: Baseline and 4-weeks
Change in blood pressure
Systolic and diastolic blood pressure (mmHg) was documented at baseline and during 4 additional weekly follow-up visits
Time frame: Baseline, follow-up weeks 1-4
Change in heart rate
Heart rate (beats/min) was documented at baseline and during 4 additional weekly follow-up visits
Time frame: Baseline, follow-up weeks 1-4
Change in waist circumference
Waist circumference (cm) was documented at baseline and during 4 additional weekly follow-up visits
Time frame: Baseline, follow-up weeks 1-4
Change in serum total cholesterol
Serum total cholesterol (mg/dL) was documented at baseline and after 4-weeks
Time frame: Baseline and 4-weeks
Change in serum high-density lipoprotein cholesterol
Serum HDL (mg/dL) was documented at baseline and after 4-weeks
Time frame: Baseline and 4-weeks
Change in serum triglycerides
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Triglycerides mg/dL was documented at baseline and after 4-weeks
Time frame: Baseline and 4-weeks
Change in serum insulin
Insulin (uU/mL) was documented at baseline and after 4-weeks
Time frame: Baseline and 4-weeks
Change in serum glucose
Serum glucose (mg/dL) was documented at baseline and after 4-weeks
Time frame: Baseline and 4-weeks
Change in serum hemoglobin A1c (HgA1c)
HgA1c (%) was documented at baseline and after 4-weeks
Time frame: Baseline and 4-weeks
Change in c-reactive protein (CRP)
CRP (mg/L) was documented at baseline and after 4-weeks
Time frame: Baseline and 4-weeks
Change in medication use
Medication needs were assessed weekly
Time frame: Baseline, follow-up weeks 1-4