The purpose of this study is to investigate the effects of a combined vitamin D and magnesium supplementation on parathyroid hormone and cardiometabolic health in persons living with obesity.
Individuals living with obesity are at a higher risk of cardiometabolic abnormalities and high circulating parathyroid hormone. There is evidence suggesting that vitamin D may play a role in cardiovascular health outcomes; however, the research is currently inconclusive. Magnesium is a cofactor of vitamin D metabolism, and the prevalence of concurrent vitamin D and magnesium deficiency is high. This study aims to investigate the effect of vitamin D and magnesium supplements in individuals who are overweight and obese on parathyroid hormone and cardiometabolic health.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
TRIPLE
Enrollment
109
Daily vitamin D and magnesium supplements are given to participants daily for 12 weeks.
Daily vitamin D supplements are given to participants daily for 12 weeks.
Daily placebo are given to participants daily for 12 weeks.
Drexel University Nutrition Sciences Research Lab
Philadelphia, Pennsylvania, United States
Serum parathyroid hormone
Time frame: 12 weeks
Inflammatory cytokines
Time frame: 12 weeks
Lipid profile
Time frame: 12 weeks
Blood pressure
Time frame: 12 weeks
Serum osteocalcin
Time frame: 12 weeks
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