To investigate biomarker reflects systemic or specific organ perfusion well, we are going to the observational comparison study using several hemodynamic monitoring methods in the premature infants. It includes near-infrared spectroscopy (NIRS), pulse oximetry with perfusion index (PI) and pleth variability index (PVI) and functional echocardiography.
Hemodynamic observational comparisons will be performed in 6 episodes below on each patient. 1. first 24 hours after birth 2. during red blood cell (RBC) transfusion: from 4 hours before to 4 hours after the transfusion 3. suspicion of necrotizing enterocolitis: from the suspicion point for 48 hours 4. suspicion of sepsis: from the suspicion point for 48 hours 5. oligouria (\< 1 mL/kg/hour of urine): for 48 hours 6. hypotension (mean blood pressure \< 30 mmHg): for 48 hours
Study Type
OBSERVATIONAL
Enrollment
85
1. NIRS, INVOS 5100 cerebral/somatic oximeter monitor (Somanetics Corp, Troy, Michigan, USA) 2. Radical-7 pulse oximeter (Masimo Corp, Irvine, CA, USA) 3. Echocardiography (Phillips HD 15 Ultrasound system, CA, USA)
Inha University Hospital
Incheon, South Korea
Positive predictive value of each index on hypotension
Positive predictive value of each index which are recorded through the monitoring machines
Time frame: first 24 hours after birth
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