Percutaneous Ethanol Alcohol Injection for the Large and Unresectable Hepatocellular Carcinoma

Inclusion Criteria: * Review and sign informed consent; * Between 15 and 80 years of age at time of trial enrollment; * Documented pathological and/or radiological diagnosis of hepatocellular carcinoma; * Radiologically documented tumor size of \> 5 centimeters; * Radiologically documented liver cirrhosis. Exclusion Criteria: * American Anesthesia Association (ASA) Class IV or V and/or any * contraindications to general anesthesia; * Uncontrollable ascites; * Deep persistent jaundice; * Hepatic encephalopathy; * Coagulopathy; * Severe thrombocytopenia; * Unable or unwilling to attend follow up visits and examinations; * Other associated surgical procedure;