Interest of Pulse Wave Velocity Measurement as a Predictor of Severity of Aortic Stenosis

Centre Hospitalier Universitaire, Amiens

Overview

Aortic valve pathology is the third most common cardiovascular disease after coronary artery disease and hypertension, which is responsible for severe morbidity and mortality in elderly patients and requires surgical treatment in its most severe form of progression. The purpose of this study is to find a link between arterial stiffness and degenerative aortic stenosis. If this link is established, arterial stiffness may become a medical therapeutic target in order to delay the evolution of the disease.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

OTHER

Masking

NONE

Conditions

Pulse Wave Aortic Stenosis

Interventions

Study the relationship between the arterial rigidity of large vessels and the presence and severity of degenerative aortic constrictionOTHER

Study the relationship between the arterial rigidity of large vessels and the presence and severity of degenerative aortic constriction

Control group without heart diseaseOTHER

Control group without heart disease

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients over 18 years of age, without legal protection (guardianship or curatorship), * Stable hemodynamic status. * Affiliation to a social security scheme Exclusion Criteria: * Hemodynamically unstable patients: Systolic PA \<10 cmHg, rapid peripheral pulse and spinning, mottling, obnubilation, oliguria, sweating, coma * History of significant valvulopathy other than an aortic stenosis, * Pregnancy. * Patient under tutelage or curatelle or deprived of public right.

Locations (1)

CHU Amiens Picardie

Amiens, Picardie, France

Outcomes

Primary Outcomes

Analysis of echocardiographic measurements of possible differences between average VOP and Sao i in terms of RA severities

Time frame: 10 years

Data from ClinicalTrials.gov

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