Effect of Suction Drains in Total Knee Arthroplasty With Tranexamic Acid

Centre hospitalier de l'Université de Montréal (CHUM)140 enrolled

Overview

Problem Suction drains during TKA present certain costs to the health system and requires additional nursing care. There is no clear evidence that supports their use, and no studies so far have compared blood loss in patients with or without drains when TA is administered during TKA. Hypothesis During total knee arthroplasty, the postoperative blood loss, measured by hemoglobin level, will be lower when no drains are used. Method * Randomized controlled trial * Monocentric, 3 surgeons * Randomisation by sealed envelopes

During total knee arthroplasty, the postoperative blood loss, measured by hemoglobin level, will be lower when no drains are used.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

140

Conditions

Arthroplasty, Replacement, Knee

Interventions

drainageDEVICE

Administration of IV tranexamic acid at the moment of anesthetic induction (1g) and at tourniquet release (1g), installing a suction drain

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Unilateral primary total knee arthroplasty Exclusion Criteria: * TKA revision * Bilateral TKA * Patients that refuse transfusions * Contraindication to tranexamic acid use: allergy, thromboembolic history * Coagulopathy * Kidney failure

Locations (1)

Centre Hospitalier de l'Université de Montréal (CHUM)

Montreal, Quebec, Canada

Outcomes

Primary Outcomes

Hb variation

Difference between Hb levels measured in pre-op and on postoperatively day 3.

Time frame: 3 days after surgey