Comparing the beneficial effect of cord milking versus deferred cord clamping in preterm neonates. A randomized controlled trial
Placental transfusion either by deferred cord clamping or umbilical cord milking became standard care and recommended management especially in preterm deliveries.1 In average, about 80 ml of blood was found to be transferred to the neoborn by one minute after birth.2 This additional blood can afford extra iron and blood volume giving the benefit of less iron deficiency anemia during the first year of life, less need for blood transfusion, less need for vasopressors and less intraventricular hemorrhage (IVH) by 50%.3 Placental transfusion with different techniques proved safety with no significant risks regarding postpartum hemorrhage, polycythemia, jaundice, Apgar score or admission rates.4 Our study aims to compare delayed cord clamping with umbilical cord milking as the best way for placental transfusion for preterm neonates.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Enrollment
200
delay of cord clamping for 60 seconds
active cord milking 5 times
Armed Forces Hospital of Southern Region
Khamis Mushait, Saudi Arabia
hematological parameters of the premature neonates
first draw and peak hematocrit value and hemoglobin percent, need for inotropes and blood transfusion
Time frame: 12 months
composite neonatal morbidities
incidence of intraventricular hemorrhage, necrotizing enterocolitis, retinopathy, jaundice, sepsis , patent ductus arteriosus, etc
Time frame: 12 month
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