The overall goal of the outlined study is to scrutinize and to promote mindfulness via new technologies using a combination of smartphone-based assessment and micro-interventions, fMRI and real-time fMRI-neurofeedback.
The overall goal of the outlined study is to scrutinize and to promote mindfulness via new technologies using a combination of smartphone-based assessment and micro-interventions, fMRI and real-time fMRI-neurofeedback. More specifically, we aim to i) evaluate whether smartphone-based micro-interventions affect mindfulness, stress, and mood, ii) evaluate whether mindfulness, its neural substrate, and related mental and physiological functions can be modified by training volitional control over brain activity by means of real-time functional magnetic resonance imaging neurofeedback (RT-fMRI-NF), iii) differentiate neural activation patterns during mindfulness vs. mind wandering.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Enrollment
84
Subjects are provided with smartphone-based mindfulness intervention.
Subjects are provided with contingent RT-fMRI-NF of their own brain activity.
Subjects are provided with sham RT-fMRI-NF of brain activity of previously recorded subject.
Korea University
Seoul, South Korea
University of Basel
Basel, Switzerland
Blood oxygenation level dependent (BOLD) Signal assessed by MRI
Blood oxygenation level dependent (BOLD) signal assessed via functional magnetic resonance imaging
Time frame: On 1 day, which is the laboratory assessment day (scheduled 1 day subsequent to the last of the 10 smartphone-based micro-intervention days)
State mindfulness assessed by State Mindfulness Scale
State mindfulness, assessed via State Mindfulness Scale (SMS)
Time frame: Daily, during smartphone-based micro-interventions (duration: 10 days); on 1 day, which is the laboratory assessment day (scheduled 1 day subsequent to the last smartphone-based micro-intervention days)
Subjective stress reactivity assessed by Visual Analog Scale
Subjective stress reactivity, assessed via Visual Analog Scale (VAS)
Time frame: Daily, during smartphone-based micro-interventions (duration: 10 days); on 1 day, which is the laboratory assessment day (scheduled 1 day subsequent to the last smartphone-based micro-intervention days)
Subjective mood assessed by Multidimensional Mood State Questionnaire
Subjective mood, assessed via Multidimensional Mood State Questionnaire (MDMQ)
Time frame: Daily, during smartphone-based micro-interventions (duration: 10 days); on 1 day, which is the laboratory assessment day (scheduled 1 day subsequent to the last smartphone-based micro-intervention days)
Emotional reactivity assessed by emotion recognition task
Assessed via emotion recognition task
Time frame: On 1 day, which is the laboratory assessment day (scheduled 1 day subsequent to the last of the 10 smartphone-based micro-intervention days)
Working Memory assessed by N-back task test
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Subjects are provided with smartphone-based mind wandering intervention.
Assessed via N-back task (visual single-3-back with letters as stimuli)
Time frame: On 1 day, which is the laboratory assessment day (scheduled 1 day subsequent to the last of the 10 smartphone-based micro-intervention days)
Cognitive flexibility assessed by computer version of Wisconsin card sorting Task test
Assessed via computer version of Wisconsin card sorting task (WCST)
Time frame: On 1 day, which is the laboratory assessment day (scheduled 1 day subsequent to the last of the 10 smartphone-based micro-intervention days)