Systemic Nalbuphine Versus Intravenous Regional Anesthesia

N/ACompletedNCT03150732

Assiut University82 enrolled

Overview

Comparison of systemic nalbuphine versus intravenous regional anesthesia in patients undergoing hand surgery.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

QUADRUPLE

Enrollment

Conditions

Postoperative Pain

Interventions

Systemic nalbuphineDRUG

Patients will receive systemic nalbuphine 10 mg

Local nalbuphineDRUG

Patients will receive local nalbuphine 10 mg

Eligibility

Sex: ALLMin age: 20 YearsMax age: 50 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients scheduled for elective unilateral hand surgery. Exclusion Criteria: * Patient refusal. * Allergy to study medications * Body mass index \> 35 kg/ m2 * Patients with sickle cell or Reynaud diseases * Patients with a history of psychiatric illness or on chronic opioids

Locations (1)

Mohamed H Bakri

Asyut, Egypt

Outcomes

Primary Outcomes

Duration of postoperative Analgesia

minutes

Time frame: Postoperative 24 hours

Secondary Outcomes

Diclofenac analgesic consumption

Time frame: Postoperative 24 hours

Cortisol level

Level of cortisone in blood (nmol/L)

Time frame: Preoperative and at 4 hours after skin incision

Severity of postoperative Pain

Visual Analogue Scale (VAS)

Time frame: Postoperative 24 hours

Data from ClinicalTrials.gov

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